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Jun Han Selected Research

Prion Proteins

8/2022Activation of Innate Immunity and Autophagy in Brain Tissues with Prion Disease and Degradation of Abnormal PrPs in Cells - China's Studies.
1/2017Protein Misfolding Cyclic Amplification Cross-Species Products of Mouse-Adapted Scrapie Strain 139A and Hamster-Adapted Scrapie Strain 263K with Brain and Muscle Tissues of Opposite Animals Generate Infectious Prions.
10/2016Proteomic Analyses for the Global S-Nitrosylated Proteins in the Brain Tissues of Different Human Prion Diseases.
8/2013Comparative analysis of gene expression profiles between cortex and thalamus in Chinese fatal familial insomnia patients.
5/2013Rare V203I mutation in the PRNP gene of a Chinese patient with Creutzfeldt-Jakob disease.
3/2013Global transcriptional profiling of the postmortem brain of a patient with G114V genetic Creutzfeldt-Jakob disease.
2/2012The diversities of PrP(Sc) distributions and pathologic changes in various brain regions from a Chinese patient with G114V genetic CJD.
7/2011The first Chinese case of Creutzfeldt-Jakob disease patient with R208H mutation in PRNP.
4/2011A Chinese Creutzfeldt-Jakob disease patient with E196K mutation in PRNP.
1/2011Familial CJD associated PrP mutants within transmembrane region induced Ctm-PrP retention in ER and triggered apoptosis by ER stress in SH-SY5Y cells.
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Jun Han Research Topics

Disease

78Neoplasms (Cancer)
01/2024 - 12/2002
53Infections
03/2024 - 09/2003
31Prion Diseases (Transmissible Spongiform Encephalopathies)
10/2023 - 08/2005
26Inflammation (Inflammations)
10/2023 - 10/2008
22Hepatocellular Carcinoma (Hepatoma)
05/2024 - 06/2006
18Scrapie
08/2022 - 03/2004
13Cachexia
01/2024 - 05/2015
13Stomach Neoplasms (Stomach Cancer)
01/2024 - 12/2002
12Neoplasm Metastasis (Metastasis)
01/2023 - 02/2008
10Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)
04/2015 - 10/2008
9Virus Diseases (Viral Diseases)
11/2023 - 10/2015
8Cholestasis
02/2024 - 01/2017
6COVID-19
01/2024 - 01/2020
6Breast Neoplasms (Breast Cancer)
08/2022 - 01/2015
6Colonic Neoplasms (Colon Cancer)
01/2022 - 08/2014
5Heart Failure
01/2024 - 09/2016
5Reperfusion Injury
12/2023 - 01/2015
5Coinfection
09/2023 - 10/2015
5Hyperglycemia
06/2023 - 04/2015
5Hemorrhage
01/2023 - 10/2008
5Hypoxia (Hypoxemia)
09/2022 - 10/2008
5Brain Ischemia (Cerebral Ischemia)
07/2022 - 01/2013
5Obesity
01/2020 - 04/2015
5Fibrosis (Cirrhosis)
01/2020 - 01/2017
5Neurodegenerative Diseases (Neurodegenerative Disease)
07/2009 - 09/2006
4Liver Neoplasms (Liver Cancer)
05/2024 - 12/2002
4Sepsis (Septicemia)
03/2024 - 01/2017
4Lung Injury
03/2024 - 07/2010
4Insulin Resistance
06/2023 - 08/2015
4Type 2 Diabetes Mellitus (MODY)
01/2023 - 08/2015
4Lung Neoplasms (Lung Cancer)
12/2022 - 01/2017
4Experimental Arthritis
10/2022 - 07/2020
4Communicable Diseases (Infectious Diseases)
08/2022 - 06/2005
4Alzheimer Disease (Alzheimer's Disease)
01/2022 - 09/2006
4Carcinoma (Carcinomatosis)
01/2022 - 06/2003
4Diarrhea
12/2021 - 01/2017
4Nasopharyngeal Carcinoma
08/2021 - 10/2009
4Atrophy
07/2021 - 05/2015
4Acute Lung Injury
04/2021 - 01/2020
4Papillary Thyroid Cancer
01/2021 - 06/2017
4Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 06/2008
4Arthritis (Polyarthritis)
01/2021 - 07/2020
4Ischemia
08/2020 - 04/2012
4Neuroblastoma
01/2020 - 09/2006
4Liver Diseases (Liver Disease)
01/2020 - 06/2016
4Portal Hypertension
12/2016 - 12/2005
4Fatal Familial Insomnia
10/2016 - 10/2008
3Brain Injuries (Brain Injury)
04/2024 - 11/2021
3Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
03/2024 - 01/2020
3Colitis
01/2024 - 01/2016
3Weight Loss (Weight Reduction)
01/2024 - 10/2022
3Sarcopenia
10/2023 - 06/2016

Drug/Important Bio-Agent (IBA)

51Proteins (Proteins, Gene)FDA Link
03/2024 - 09/2006
23Biomarkers (Surrogate Marker)IBA
02/2024 - 07/2010
18Prion ProteinsIBA
08/2022 - 09/2006
13VaccinesIBA
12/2023 - 02/2008
11Interleukin-6 (Interleukin 6)IBA
01/2024 - 10/2012
11EnzymesIBA
10/2023 - 10/2010
11CytokinesIBA
01/2023 - 03/2013
10Glucose (Dextrose)FDA LinkGeneric
04/2024 - 09/2013
10Antiviral Agents (Antivirals)IBA
03/2024 - 02/2016
10MicroRNAs (MicroRNA)IBA
10/2023 - 08/2014
10PrionsIBA
10/2023 - 08/2005
9LipidsIBA
01/2024 - 01/2013
8Messenger RNA (mRNA)IBA
01/2023 - 10/2012
7PlatinumIBA
08/2022 - 01/2019
7RNA (Ribonucleic Acid)IBA
01/2022 - 01/2018
7Protein Isoforms (Isoforms)IBA
12/2017 - 09/2006
6LipopolysaccharidesIBA
03/2024 - 01/2020
6Bile Acids and Salts (Bile Acids)IBA
02/2024 - 01/2017
6Oxygen (Dioxygen)IBA
01/2023 - 03/2004
6Long Noncoding RNAIBA
01/2022 - 01/2019
6Codon (Codons)IBA
01/2021 - 12/2008
6Phosphotransferases (Kinase)IBA
08/2020 - 04/2010
5Transcription Factors (Transcription Factor)IBA
05/2024 - 09/2016
5Peptides (Polypeptides)IBA
03/2024 - 05/2012
5Insulin (Novolin)FDA Link
06/2023 - 08/2015
5Therapeutic UsesIBA
01/2023 - 09/2016
5DNA (Deoxyribonucleic Acid)IBA
08/2022 - 12/2016
5AlbuminsIBA
01/2021 - 11/2019
5Methionine (L-Methionine)FDA Link
01/2020 - 12/2008
5Endopeptidase K (Proteinase K)IBA
01/2017 - 08/2005
4Amino AcidsFDA Link
12/2023 - 01/2009
4Sirtuin 1IBA
10/2023 - 10/2020
4BilirubinIBA
07/2023 - 02/2020
4Hormones (Hormone)IBA
01/2023 - 04/2011
4Cisplatin (Platino)FDA LinkGeneric
12/2021 - 01/2019
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021 - 02/2008
4Glycoproteins (Glycoprotein)IBA
11/2019 - 07/2012
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2018 - 10/2014
3Polysaccharides (Glycans)IBA
02/2024 - 10/2022
3Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
12/2023 - 10/2006
3HydrogenIBA
11/2023 - 01/2013

Therapy/Procedure

33Therapeutics
07/2023 - 09/2012
8Drug Therapy (Chemotherapy)
10/2023 - 01/2012
8Radiotherapy
01/2023 - 10/2009
5Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated)
04/2024 - 09/2012
4Hepatectomy
05/2024 - 09/2016
4Photochemotherapy (Photodynamic Therapy)
08/2022 - 01/2019
4Lasers (Laser)
08/2022 - 01/2016